AmitAuthor of the NonBioS engineering postNonBioS
NonBioS's AI engineer product, whose runs use over a million tokens and about a hundred inference calls in five minutes, with sensitive customer data.
Its own announcement, published Read the write-up (opens the announcement in a new tab)
Observation
NonBioS ruled out LangSmith because it seemed tightly coupled to LangChain, which the team had removed from its code, and chose Langfuse.
- Takeaway
- If your code has left LangChain, test LangSmith through its SDK wrappers or OpenTelemetry before you rule it out on coupling alone.
- What happened
- NonBioS had found LangChain too complex and rewritten its systems without it, so it declined LangSmith as strongly coupled to LangChain (Mar 5, 2025). It looked at Arize Phoenix briefly and found the naming and website confusing, narrowed the field to Langfuse and Helicone, and chose Langfuse for session tracking that groups a run's calls into one session, self-hosting and open-source extensibility.
“Langsmith appeared popular, but we had encountered challenges with Langchain from the same company, finding it overly complex for previous NonBioS tooling. We rewrote our systems to remove dependencies on Langchain and chose not to proceed with Langsmith as it seemed strongly coupled with Langchain.”
- Public engineering write-up
- No team metrics reported
Deployment details
NonBioS's AI engineer product, whose runs use over a million tokens and about a hundred inference calls in five minutes, with sensitive customer data.
- Public engineering write-up
- No team metrics reported
- Team
- NonBioS engineering
- Workload
- Long agent runs with about a hundred inference calls each
- Product version
- Evaluated and passed over








